Prevalence of germline variants in Brazilian pancreatic carcinoma patients.

doi:10.1038/s41598-024-71884-4

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Article

Prevalence of germline variants in Brazilian pancreatic carcinoma patients.

Scientific reports - 10 Sept 2024

Rodrigues Lívia Munhoz, Maistro Simone, Katayama Maria Lucia Hirata, Rocha Vinícius Marques, Lopez Rossana Veronica Mendoza, Lopes Edia Filomena di Tullio, Gonçalves Fernanda Toledo, Fridman Cintia, Serio Pedro Adolpho de Menezes Pacheco, Barros Luciana Rodrigues Carvalho, Leite Luiz Antonio Senna, Segatelli Vanderlei, Estevez-Diz Maria Del Pilar, Guindalini Rodrigo Santa Cruz, Ribeiro Junior Ulysses, Folgueira Maria Aparecida Azevedo Koike

Abstract excerpt

We evaluated the prevalence of pathogenic/likely pathogenic germline variants (PGV) in Brazilian pancreatic adenocarcinoma (PC) patients, that represent a multiethnic population, in a cross-sectional study. We included 192 PC patients unselected for family history of cancer. We evaluated a panel of 113 cancer genes, through genomic DNA sequencing and 46 ancestry-informative markers, through multiplex PCR. The...

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Identifiers

PMID: 39256447
DOI: 10.1038/s41598-024-71884-4
PMCID: PMC11387492

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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