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Article

BPSS: a Nextflow pipeline for Bacterial Peptide Sequence Selection to detect protein diversity.

Bioinformatics (Oxford, England) - 2 Jan 2026

Bastien Sylvère, François Pauline, Moussadeq Sara, Lemoine Jérôme, Moreau Karen, Vandenesch François

Abstract excerpt

MOTIVATION: Sequence variability can be extremely high, particularly in bacteria due to the rapid accumulation of mutations linked to their high replication rate and environmental selection pressure, which often favors diversifying selection. For most species, there are no automated, computationally efficient tools available for constructing a nonredundant database covering the allelic variability of target...

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Topics

Software
Bacterial Proteins
Peptides
Sequence Analysis, Protein
Amino Acid Sequence
Databases, Protein

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Genetic Variation

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Identifiers

PMID: 41450201
DOI: 10.1093/bioinformatics/btaf677
PMCID: PMC12797209

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