MultiStageSearch: a multi-step proteogenomic workflow for taxonomic identification of viral proteome samples adressing database bias

Abstract excerpt

The recent years, with the global SARS-Cov-2 pandemic, have shown the importance of strain level identification of viral pathogens. While the gold-standard approach for unkown viral sample identification remains genomics, studies have shown the necessity and advantages of orthogonal experimental approaches such as proteomics, based on proteomic database search methods. The databases required as references for both...

Topics

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• Bacteriophages and microbial interactions
• Genomics and Phylogenetic Studies
• Machine Learning in Bioinformatics
• SARS-CoV-2 and COVID-19 Research
• SARS-CoV-2 detection and testing
• vaccines and immunoinformatics approaches
• Viral gastroenteritis research and epidemiology
• Virus-based gene therapy research

Identifiers and source

Literature Corpus work

0974b4b6-71cb-5b0d-8548-80c9c456f3e9

DOI

10.1101/2024.05.15.594287