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Article

Trans-ethnic conditional-likelihood Mendelian randomization reveals novel causal links between depression and allergic rhinitis/asthma across five global ancestries.

European archives of psychiatry and clinical neuroscience - 1 Jun 2026

Zeng Bo, Zhou Chaoqun, Li Li, Zhu Yongbo

Abstract excerpt

OBJECTIVE: Major depressive disorder (MDD) frequently co-occurs with asthma and allergic rhinitis (AR); however, the causal directions and ancestral differences remain incompletely understood. This study integrates genome-wide association study data from European (EUR), East Asian (EAS), South Asian (SAS), Hispanic (HIS), and African (AFR) ancestries, employing the trans-ethnic Mendelian randomization (TEMR)...

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PMID: 41432739
DOI: 10.1007/s00406-025-02175-w

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AR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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