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Article

Causal role of immune cells in allergic rhinitis: A bidirectional Mendelian randomization study.

Brazilian journal of otorhinolaryngology - 1 Jan 2026

Tan Yuhan, Hu Xiaoyan, Zhang Jing, Wan Shuoyu, Jiang Liang

Abstract excerpt

OBJECTIVE: Previous observational studies have indicated an association between various immune cells and allergic rhinitis; however, the causal relationship remains uncertain. This study seeks to further investigate the causal link between immune cells and allergic rhinitis through bidirectional two-sample Mendelian randomization analysis. METHODS: Allergic rhinitis related data were obtained from the MRC-IEU...

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Topics

Humans
Rhinitis, Allergic
Mendelian Randomization Analysis
Genome-Wide Association Study
Phenotype
Reproducibility of Results

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Genetic Predisposition to Disease

Polymorphism, Single Nucleotide

Source

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Identifiers

PMID: 41138280
DOI: 10.1016/j.bjorl.2025.101726
PMCID: PMC12594888

Genes

AR

Provenance

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