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Article

Causal role of 731 immune cell types in atrial fibrillation: A bidirectional two-sample Mendelian randomization study.

Medicine - 19 Dec 2025

Huang Luofei, Li Han, Lin Quanzhi, Shi Jian

Abstract excerpt

Mounting genetic evidence indicates that immune dysregulation may be a key driver in the development of atrial fibrillation (AF), yet the specific immune pathways involved remain poorly characterized. In this study, we applied advanced Mendelian randomization approaches to systematically assess the causal relationships between 731 precisely defined immune cell traits and susceptibility to AF. By integrating...

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Identifiers

PMID: 41431094
DOI: 10.1097/MD.0000000000046767
PMCID: PMC12727287

Genes

CD38

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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