Article
Effect of the rs7858836 Single-Nucleotide Polymorphisms of the ASTN2 Gene on Pain-Related Phenotypes in Japanese Women Who Underwent Laparoscopic Gynecologic Surgery.
Neuropsychopharmacology reports - 1 Mar 2026
Inoue Rie, Nishizawa Daisuke, Okahara Shoko, Hara Atsuko, Okada Hisako, Hasegawa Junko, Ebata Yuko, Nakayama Kyoko, Hayashida Masakazu, Ikeda Kazutaka
Abstract excerpt
BACKGROUND: In our previous study, the minor T allele of the rs7858836 C/T single-nucleotide polymorphism (SNP) in the ASTN2 gene, which encodes astrotactin 2, was associated with reduced fentanyl requirements after laparoscopic-assisted colectomy and after mandibular osteotomy. In this study, we investigated the effects of this SNP on pain-related phenotypes in patients who underwent laparoscopic gynecologic...
Topics
Join the communities discussing this publication.