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Article

Causal Effect of Type 1 Diabetes on Juvenile Idiopathic Arthritis and the Mediating Role of CD8+ Natural Killer T Cells.

The Journal of clinical endocrinology and metabolism - 19 May 2026

Chen Jinlin, Wu You, Li Feng, Guo Qian

Abstract excerpt

CONTEXT: Emerging observational evidence has suggested a comorbidity between type 1 diabetes (T1D) and juvenile idiopathic arthritis (JIA). OBJECTIVE: The study aimed to evaluate the causal effect of T1D on JIA, explore the mediating role of circulating immune cells, and verify the causal relationship in mouse models. METHODS: We first assessed the genetic correlation using linkage disequilibrium score...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 41396850
DOI: 10.1210/clinem/dgaf664

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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