Article
Association between type 1 diabetes and systemic lupus erythematosus: a Mendelian randomization study.
Clinical rheumatology - 1 Jan 2024
Liu Shulin, Si Shucheng, Li Jiqing, Zhao Yingqi, Yu Qingqing, Xue Fuzhong
Abstract excerpt
OBJECTIVES: Observational studies have shown that there is a bidirectional relationship between type 1 diabetes (T1D) and systemic lupus erythematosus (SLE); the causality of this association remains elusive and may be affected by confusion and reverse causality. There is also a lack of large-scale randomized controlled trials to verify. Therefore, this Mendelian randomization (MR) study aimed to investigate the...
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