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Endoplasmic reticulum membrane complex 1 facilitates BK polyomavirus genotype III/IV replication for nephropathy.

Biochemical and biophysical research communications - 8 Jan 2026

Fukae Shota, Nakazawa Shigeaki, Matsumura Soichi, Tanaka Ryo, Kawamura Masataka, Kishikawa Hidefumi, Kato Taigo, Kakuta Yoichi, Nonomura Norio

Abstract excerpt

BK polyomavirus nephropathy (BKPyVN) remains a major cause of renal allograft dysfunction. However, the influence of viral genotype on disease progression and host-virus interactions is not fully understood. We examined kidney transplant recipients presenting with urinary decoy cells and categorized them into asymptomatic BKPyV viruria and biopsy-confirmed BKPyVN. Genotyping of the VP1 region revealed that all...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 41371185
DOI: 10.1016/j.bbrc.2025.153063

Genes

EMC1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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