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Article

A diverse virome in kidney transplant patients contains multiple viral subtypes with distinct polymorphisms.

Scientific reports - 16 Sept 2016

Rani Asha, Ranjan Ravi, McGee Halvor S, Metwally Ahmed, Hajjiri Zahraa, Brennan Daniel C, Finn Patricia W, Perkins David L

Abstract excerpt

Recent studies have established that the human urine contains a complex microbiome, including a virome about which little is known. Following immunosuppression in kidney transplant patients, BK polyomavirus (BKV) has been shown to induce nephropathy (BKVN), decreasing graft survival. In this study we investigated the urine virome profile of BKV+ and BKV- kidney transplant recipients. Virus-like particles were...

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Identifiers

PMID: 27633952
DOI: 10.1038/srep33327
PMCID: PMC5025891

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