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Article

Aripiprazole and CYP2D6: A retrospective cohort study evaluating the impact of phenotype on metabolic abnormalities.

American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists - 26 May 2026

Meissner Brian R, Younes Fatme, Massmann Amanda, Weaver Max, Petry Natasha J

Abstract excerpt

PURPOSE: The aim of this study was to investigate the influence of CYP2D6 functionality on metabolic abnormalities in patients prescribed aripiprazole. METHODS: A retrospective cohort review was conducted in patients who had CYP2D6 genotyping and an oral prescription for aripiprazole. Primary outcomes were changes in metabolic parameters from baseline based on CYP2D6 genotype-based phenotype. Patients...

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Antipsychotic Agents
Cohort Studies
Cytochrome P-450 CYP2D6
Cytochrome P-450 CYP2D6 Inhibitors

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Metabolic Diseases

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PMID: 41364071
DOI: 10.1093/ajhp/zxaf345

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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