Article
Molecular epidemiology and transmission dynamics of multi-drug resistant tuberculosis strains using whole genome sequencing in the Amhara region, Ethiopia.
BMC genomics - 17 Jul 2023
Shibabaw Agumas, Gelaw Baye, Ghanem Mostafa, Legall Noah, Schooley Angie M, Soehnlen Marty K, Salvador Liliana C M, Gebreyes Wondwossen, Wang Shu-Hua, Tessema Belay
Abstract excerpt
BACKGROUND: Drug resistant Mycobacterium tuberculosis prevention and care is a major challenge in Ethiopia. The World health organization has designated Ethiopia as one of the 30 high burden multi-drug resistant tuberculosis (MDR-TB) countries. There is limited information regarding genetic diversity and transmission dynamics of MDR-TB in Ethiopia. OBJECTIVE: To investigate the molecular epidemiology and...
Topics
- Humans
- Antitubercular Agents
- Tuberculosis
- Mycobacterium tuberculosis
- Ethiopia
- Molecular Epidemiology
- Tuberculosis, Multidrug-Resistant
- Genotype
- Whole Genome Sequencing
- Minisatellite Repeats
