Article
Novel polygenic risk score associates with diverticulitis in a multi-institutional, ancestrally diverse cohort.
Scientific reports - 27 Nov 2025
Neylan Christopher J, Ueland Thomas, Abramowitz Sarah A, DePaolo John S, Tsao Noah L, Roberson Jeffrey L, Hawkins Alexander T, Carey David J, Smelser Diane T, Levin Michael G, Hoffman Rebecca L, Damrauer Scott M, Maguire Lillias H
Abstract excerpt
Diverticulitis is a common and morbid colorectal disease that recurs after an initial attack in up to 30% of patients. Elective surgery to remove the affected portion of the colon is an effective intervention to prevent disease recurrence, but appropriate patient selection is challenging given the limited ability to predict which patients are likely to recur, or the severity with which they may do so. Genetics...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.