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Article

Late-onset intracranial adenocarcinoma arising from a germ cell tumor 25 years after initial diagnosis.

Brain tumor pathology - 1 Jul 2026

Yamagiwa Yuri, Nomura Masashi, Takami Hirokazu, Kondo Atsushi, Kitagawa Yosuke, Shinozaki-Ushiku Aya, Takayanagi Shunsaku, Saito Nobuhito

Abstract excerpt

A teratoma with somatic-type malignancy is a rare subtype of germ cell tumor (GCT) characterized by the presence of a histologically distinct component resembling a somatic cancer within a teratoma feature. To date, only 14 cases have been reported in the central nervous system (CNS), and its diagnosis remains challenging due to the limited availability of pathological findings. A case of a pineal GCT that...

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Identifiers

PMID: 41291281
DOI: 10.1007/s10014-025-00522-2
PMCID: PMC13375961

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