Phenotypic dominance emerges from activity fitness functions and molecular interactions.

Abstract excerpt

Mendelian genetics provides us with a framework for studying allelic dominance relationships at a locus at the phenotypic level. These dominance relationships result from different molecular factors, including the mapping of molecular activity onto fitness. For homomeric proteins, physical interactions between alleles provide a mechanism by which 1 allele can have a dominant effect on the activity of the other....

Topics

• Phenotype
• Genetic Fitness
• Genes, Dominant
• Models, Genetic
• Alleles
• Protein Multimerization