Article
Gene expression drives the evolution of dominance.
Nature communications - 16 Jul 2018
Huber Christian D, Durvasula Arun, Hancock Angela M, Lohmueller Kirk E
Abstract excerpt
Dominance is a fundamental concept in molecular genetics and has implications for understanding patterns of genetic variation, evolution, and complex traits. However, despite its importance, the degree of dominance in natural populations is poorly quantified. Here, we leverage multiple mating systems in natural populations of Arabidopsis to co-estimate the distribution of fitness effects and dominance...
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