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Potential Therapeutic Targets for Neuroblastoma Screened through Mendelian Randomization Analysis.

Archives of Iranian medicine - 1 Nov 2025

Yang Zhenge, Zhang Yunlong, Wang Shan

Abstract excerpt

BACKGROUND: Neuroblastoma (NB) is the most prevalent extracranial solid tumor in children. Therefore, urgent exploration of novel therapeutic targets and more effective approaches is imperative to enhance the prognosis of these children. METHODS: NB datasets were obtained from OpenGWAS-ieu-a-816 (1,627 cases; 3,254 controls; European ancestry) and prot-a-2003 (N=3,301; European ancestry)-and were combined by...

Topics

Humans
Neuroblastoma
Mendelian Randomization Analysis
Quantitative Trait Loci
Genetic Predisposition to Disease

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 41778435
DOI: 10.34172/aim.35114
PMCID: PMC12958419

Genes

BTNL2
CPNE1
DNAJC9
NBPF3
ZNF559

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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