Long-read structural variant discovery and targeted short read genotyping enables population scale characterization of structural variation in rhesus macaques.

Abstract excerpt

BACKGROUND: Due to their close evolutionary relationship with humans, rhesus macaques are an important pre-clinical model. While genetic diversity driven by short nucleotide variation has long been studied in rhesus macaques, there is comparatively little known about structural variation, with most published studies focused on cross-species comparative analyses. Understanding the degree and implications of...

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