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Article

Causal associations between environmental factors and risk of IgA nephropathy and membranous nephropathy: a bidirectional Mendelian randomization and mediation analysis

9 Apr 2025

Abstract excerpt

Aims IgA nephropathy (IgAN) and membranous nephropathy (MN) have intricate etiologies that are poorly understood. This study aimed to investigate the impact of genetically predicted environmental factors on IgAN and MN.Methods We used bidirectional two-step Mendelian randomization (MR) analysis utilizing large-scale genome-wide association study (GWAS) data to investigate the relationships between 68...

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Share to Chronic Kidney Disease and Diabetes
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PMID: 40204511
DOI: 10.1080/0886022x.2025.2486620

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