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Article

Mendelian randomization reveals the causal links between miRNAs and rheumatoid arthritis.

Medicine - 31 Oct 2025

Wei Zehong, Chen DongXu, Li LianFa, Yang Junping, Wang Ying

Abstract excerpt

Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by persistent joint inflammation and progressive structural damage, with early diagnosis remaining a significant clinical challenge. Circulating microRNAs (miRNAs) have emerged as promising biomarkers for disease diagnosis, prognosis, and therapeutic response due to their critical roles in gene regulation. However, the specific miRNAs...

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Identifiers

PMID: 41261618
DOI: 10.1097/MD.0000000000045527
PMCID: PMC12582772

Genes

BCL2
HMGA2
PPARG
SIRT1
TGFBR1
TNF
UBB

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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