Article
Merqury: reference-free quality, completeness, and phasing assessment for genome assemblies
2020-03-17
Abstract excerpt
Recent long-read assemblies often exceed the quality and completeness of available reference genomes, making validation challenging. Here we present Merqury, a novel tool for reference-free assembly evaluation based on efficient k-mer set operations. By comparing k-mers in a de novo assembly to those found in unassembled high-accuracy reads, Merqury estimates base-level accuracy and completeness. For trios, Merqu...
Topics
Open a Topic to create a Post that cites this publication.
Identifiers and source
- Literature Corpus work
- e93b4db7-fec8-5948-bfa8-b871eaaf4dbb
- DOI
- 10.1101/2020.03.15.992941