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Article

The impact of GST genetic polymorphisms on the response to oxaliplatin-based chemotherapy and survival prognosis in gastric cancer patients.

Pharmacogenomics - 1 Jan 2025

Zhang Jiaodi, Jin Qi, Chen Tao, Liu Xinyue

Abstract excerpt

AIM: This study aimed to assess the impact of GSTP1, GSTM1, and GSTT1 polymorphisms on the response to oxaliplatin-based chemotherapy and survival outcomes in gastric cancer patients from Northwest China. PATIENTS AND METHODS: Genotypes of GSTP1, GSTM1, and GSTT1 were analyzed in 185 gastric cancer patients receiving SOX/XELOX regimens. The associations of these genotypes with the objective response rate (ORR),...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 41221821
DOI: 10.1080/14622416.2025.2583728
PMCID: PMC12667671

Genes

GSTP1
GSTM1
GC
GSTT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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