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Identification of DNAH6 mutations in infertile men with multiple morphological abnormalities of the sperm flagella

1 Nov 2019

Abstract excerpt

Male infertility due to spermatogenesis defects affects millions of men worldwide. However, the genetic etiology of the vast majority remains unclear. Here we describe three men with primary infertility due to multiple morphological abnormalities of the sperm flagella (MMAF) from two unrelated Han Chinese families. We performed whole-exome sequencing (WES) and Sanger sequencing on the proband of family 1, and...

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Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
Reproductive Biology and Fertility
Sperm and Testicular Function

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 31676830
DOI: 10.1038/s41598-019-52436-7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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