Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Articular Aging and Osteoarthrosis in Dwarf Mice

7 Oct 2008

Abstract excerpt

In aging hypopituitary dwarf mice (dwdw), articular chondrocytes are poorly supplied with organelles; aggregation of collagen in the cartilaginous matrix is decreased, and aging of the articular cartilage is retarded as compared to non-dwarf mice (Dwdw or DwDw) of the same strain. Osteoarthrosis developing in 58% of male and in 22 % of female non-dwarfs was not observed in dwarfs regardless of sex. The unusually...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adipokines, Inflammation, and Metabolic Diseases
Share to Adipose Tissue and Metabolism
Share to Osteoarthritis Treatment and Mechanisms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 4119783
DOI: 10.1159/000162458

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Articular Aging and Osteoarthrosis in Dwarf MicePMID 4119783Read ↗

Prematurely aging mitochondrial DNA mutator mice display subchondral osteopenia and chondrocyte hypertrophy without further osteoarthritis featuresSemantic proximity Read ↗

Prolonged longevity of hypopituitary dwarf mice.Semantic proximity Read ↗

Aging and osteoarthritis: the role of chondrocyte senescence and aging changes in the cartilage matrixSemantic proximity Read ↗

Transmitochondrial mito-miceΔ and mtDNA mutator mice, but not aged mice, share the same spectrum of musculoskeletal disorders.Semantic proximity Read ↗

Mouse models of telomere dysfunction phenocopy skeletal changes found in human age-related osteoporosis.Semantic proximity Read ↗

Establishment of a novel dwarf rat strain: cartilage calcification insufficient (CCI) rats.Semantic proximity Read ↗

Transgenic mouse models for studying the role of cartilage macromolecules in osteoarthritis.Semantic proximity Read ↗

Delayed Occurrence of Fatal Neoplastic Diseases in Ames Dwarf Mice: Correlation to Extended LongevitySemantic proximity Read ↗

Premature aging in klotho mutant mice: cause or consequence?Semantic proximity Read ↗

Osteoarthritis: New Insights in Animal ModelsSemantic proximity Read ↗

Lifespan extension and delayed immune and collagen aging in mutant mice with defects in growth hormone productionSemantic proximity Read ↗

In vivo protective effect of adipsin-deficiency on spontaneous knee osteoarthritis in aging mice.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.