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Article

Assessing the causal associations of insomnia with depressive symptoms and subjective well-being: a bidirectional Mendelian randomization study.

Sleep medicine - 1 Nov 2021

Zhou Feixiang, Guo Yicong, Wang Zhe, Liu Siyue, Xu Huilan

Abstract excerpt

BACKGROUND: The interactions and associations between insomnia, depressive symptoms, and subjective well-being are complex, thus it is hard to explore the effect and direction of causalities. This bidirectional Mendelian randomization (MR) study was to assess the causal associations of insomnia with depressive symptoms and subjective well-being. METHODS: Summary statistics for insomnia, depressive symptoms, and...

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Source

Identifiers

PMID: 34544013
DOI: 10.1016/j.sleep.2021.08.025

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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