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Article

Causal links between mitochondrial genes, cerebrospinal fluid metabolites, and delirium: a mendelian randomization study.

Arquivos de neuro-psiquiatria - 1 Oct 2025

Wang Yafeng, Wu Jiaming, Wei Shiyang, Hu Yanyan, Li Yalan

Abstract excerpt

Mitochondrial dysfunction plays a crucial role in neuropsychiatric disorders, including delirium.To explore the causal links between mitochondrial-related druggable genes, cerebrospinal fluid metabolites, and delirium.Summary-level data on mitochondrial-related druggable genes, expression quantitative trait loci (eQTLs), 338 cerebrospinal fluid (CSF) metabolites, and delirium data were obtained from publicly...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 41330563
DOI: 10.1055/s-0045-1812892
PMCID: PMC12672120

Genes

SCP2

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