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Article

Exploring the causal relationship between delirium and sarcopenia using bidirectional two-sample Mendelian randomization study.

Progress in neuro-psychopharmacology & biological psychiatry - 2 Apr 2025

Zhou Rui, Fu Yumeng, Wan Peiling, Cheng Baoli

Abstract excerpt

BACKGROUND: Population-based studies have validated the significant associations between delirium and sarcopenia. Nonetheless, the causality remains ambiguous. This study aims to elucidate the causal associations between delirium and sarcopenia, as well as the causal effects of medication use on both conditions. METHODS: A bidirectional two-sample Mendelian randomization (MR) analysis was performed based on...

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PMID: 40081562
DOI: 10.1016/j.pnpbp.2025.111327

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