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Causality Investigation between Gut Microbiome and Sleep-Related Traits: A Bidirectional Two-Sample Mendelian Randomization Study.

Genes - 12 Jun 2024

Zhai Mingxia, Song Weichen, Liu Zhe, Cai Wenxiang, Lin Guan Ning

Abstract excerpt

Recent research has highlighted associations between sleep and microbial taxa and pathways. However, the causal effect of these associations remains unknown. To investigate this, we performed a bidirectional two-sample Mendelian randomization (MR) analysis using summary statistics of genome-wide association studies (GWAS) from 412 gut microbiome traits (N = 7738) and GWAS studies from seven sleep-associated...

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PMID: 38927705
DOI: 10.3390/genes15060769
PMCID: PMC11202894

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