Article
The Genetic Architecture of the Human Corpus Callosum and its Subregions.
Nature communications - 4 Nov 2025
Bhatt Ravi R, Gadewar Shruti P, Shetty Ankush, Ba Gari Iyad, Haddad Elizabeth, Javid Shayan, Ramesh Abhinaav, Nourollahimoghadam Elnaz, Zhu Alyssa H, de Leeuw Christiaan, Thompson Paul M, Medland Sarah E, Jahanshad Neda
Abstract excerpt
The corpus callosum (CC) is the largest set of white matter fibers connecting the two hemispheres of the brain. In humans, it is essential for coordinating sensorimotor responses and performing associative or executive functions. Identifying which genetic variants underpin CC morphometry can provide molecular insights into the CC's role in mediating cognitive processes. We developed and used an artificial...
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