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Article

Mapping Corpus Callosum Morphology in Twin Pairs Discordant for Bipolar Disorder

7 Mar 2011

Abstract excerpt

Callosal volume reduction has been observed in patients with bipolar disorder, but whether these deficits reflect genetic vulnerability to the illness remains unresolved. Here, we used computational methods to map corpus callosum abnormalities in a population-based sample of twin pairs discordant for bipolar disorder. Twenty-one probands with bipolar I disorder (mean age 44.4 ± 7.5 years; 48% female), 19 of their...

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PMID: 21383237
DOI: 10.1093/cercor/bhr030

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