Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Revealing Monogenic Diabetes: Clinical and Genetic Features of Pediatric MODY Cases in Türkiye: Single Center Experience.

Pediatric diabetes - 1 Jan 2025

Sanri Aslihan, Cetin Tugba Kontbay, Acikgoz Emel Gul, Mutlu Mehmet Burak, Sezer Ozlem

Abstract excerpt

Objective: Maturity-onset diabetes of the young (MODY) represents a genetically and clinically heterogeneous form of monogenic diabetes caused by defects in pancreatic β-cell function. Accurate molecular diagnosis is essential for distinguishing MODY from type 1 and type 2 diabetes, enabling precision-based management and targeted therapy. This study aimed to evaluate the genetic and clinical features of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adolescent
Share to Child
Share to Child, Preschool

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Diabetes Mellitus, Type 2

Share to Germinal Center Kinases

Share to High-Throughput Nucleotide Sequencing

Share to Mutation

Share to Turkey

Source

Open in PubMed Open full text

Identifiers

PMID: 41367630
DOI: 10.1155/pedi/4035026
PMCID: PMC12685419

Genes

GCK
HNF1B
CEL
HNF1A
INS
KCNJ11
PDX1
ABCC8
APPL1
HNF4A
NEUROD1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Revealing Monogenic Diabetes: Clinical and Genetic Features of Pediatric MODY Cases in Türkiye: Single Center Experience.PMID 41367630Read ↗

Molecular and Clinical Profiles of Pediatric Monogenic Diabetes Subtypes: Comprehensive Genetic Analysis of 138 PatientsSemantic proximity Read ↗

Monogenic Childhood Diabetes: Dissecting Clinical Heterogeneity by Next-Generation Sequencing in Maturity-Onset Diabetes of the Young.Semantic proximity Read ↗

Focusing on Rare Variants Related to Maturity-Onset Diabetes of the Young in Children.Semantic proximity Read ↗

Maturity onset diabetes of youth (MODY) in Turkish children: sequence analysis of 11 causative genes by next generation sequencing.Semantic proximity Read ↗

Study of ten causal genes in Turkish patients with clinically suspected maturity-onset diabetes of the young (MODY) using a targeted next-generation sequencing panel.Semantic proximity Read ↗

Genetic spectrum and treatment implications of maturity-onset diabetes of the young in the eastern Black Sea region of Türkiye: a combined adult and pediatric cohort of 296 patients with identification of rare and novel variants.Semantic proximity Read ↗

Clinical and Laboratory Characteristics of MODY Cases, Genetic Mutation Spectrum and Phenotype-genotype RelationshipSemantic proximity Read ↗

Genetic Characterization of MODY in Iranian Families Using Multigenerational-Based Whole-Exome Sequencing Approach.Semantic proximity Read ↗

Study of Thirteen Causal Genes in Turkish Patients with Clinically Suspected Maturity-Onset Diabetes of the Young (MODY) using a Targeted Next-Generation Sequencing PanelSemantic proximity Read ↗

Molecular diagnosis of maturity-onset diabetes of the young (MODY) in Turkish children by using targeted next-generation sequencing.Semantic proximity Read ↗

[Clinical characteristics and genetic analysis of children and adolescents with monogenic diabetes].Semantic proximity Read ↗

Maturity-onset diabetes of the young in a large Portuguese cohort.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.