Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Precision Diagnosis of Maturity-Onset Diabetes of the Young with Next-Generation Sequencing: Findings from the MODY-IST Study in Adult Patients.

Omics : a journal of integrative biology - 1 Apr 2022

Aydogan Hulya Yilmaz, Gul Nurdan, Demirci Deniz Kanca, Mutlu Ummu, Gulfidan Gizem, Arga Kazim Yalcin, Ozder Aclan, Camli Ahmet Adil, Tutuncu Yildiz, Ozturk Oguz, Cacina Canan, Darendeliler Feyza, Poyrazoglu Sukran, Satman Ilhan

Abstract excerpt

Maturity-onset diabetes of the young (MODY) is a highly heterogeneous group of monogenic and nonautoimmune diseases. Misdiagnosis of MODY is a widespread problem and about 5% of patients with type 2 diabetes mellitus and nearly 10% with type 1 diabetes mellitus may actually have MODY. Using next-generation DNA sequencing (NGS) to facilitate accurate diagnosis of MODY, this study investigated mutations in 13 MODY...

Topics

Join the communities discussing this publication.

Diabetes Mellitus, Type 2
High-Throughput Nucleotide Sequencing
Mutation
Mutation, Missense

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 35333605
DOI: 10.1089/omi.2022.0006

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Precision Diagnosis of Maturity-Onset Diabetes of the Young with Next-Generation Sequencing: Findings from the MODY-IST Study in Adult Patients.PMID 35333605Read ↗

Monogenic Childhood Diabetes: Dissecting Clinical Heterogeneity by Next-Generation Sequencing in Maturity-Onset Diabetes of the Young.Semantic proximity Read ↗

Targeted next generation sequencing in patients with maturity-onset diabetes of the young (MODY)Semantic proximity Read ↗

Molecular diagnosis of maturity-onset diabetes of the young (MODY) in Turkish children by using targeted next-generation sequencing.Semantic proximity Read ↗

Study of ten causal genes in Turkish patients with clinically suspected maturity-onset diabetes of the young (MODY) using a targeted next-generation sequencing panel.Semantic proximity Read ↗

The Importance of Molecular Genetic Testing for Precision Diagnostics, Management, and Genetic Counseling in MODY Patients.Semantic proximity Read ↗

Study of Thirteen Causal Genes in Turkish Patients with Clinically Suspected Maturity-Onset Diabetes of the Young (MODY) using a Targeted Next-Generation Sequencing PanelSemantic proximity Read ↗

MODY is prevalent in later-onset diabetes, has potential for targeted therapy but is challenging to identifySemantic proximity Read ↗

Targeted sequencing identifies novel variants in common and rare MODY genesSemantic proximity Read ↗

Genetic and Clinical Characterization of Patients with Maturity-Onset of Diabetes of the Young (MODY): Identification of Novel Variations.Semantic proximity Read ↗

Precision diabetes: Lessons learned from maturity-onset diabetes of the young (MODY).Semantic proximity Read ↗

Genetic Variants and Therapeutic Approaches in Maturity-Onset Diabetes of the Young: A Retrospective AnalysisSemantic proximity Read ↗

Maturity onset diabetes of youth (MODY) in Turkish children: sequence analysis of 11 causative genes by next generation sequencing.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.