Article
Culture and Adaptation of Pseudomonas aeruginosa During Early Infection in Children With Cystic Fibrosis.
The Journal of infectious diseases - 17 Jan 2026
Mitra Sumitra D, Soneji Maulin, Axline Christopher M R, Hayden Hillary S, Radey Matthew C, Forsberg Cara M, Ozer Egon A, Wolter Daniel J, Pope Christopher E, Burns Jane, Hoffman Lucas R, Mayer-Hamblett Nicole, Singh Pradeep, Hauser Alan R
Abstract excerpt
BACKGROUND: Relatively little is known about Pseudomonas aeruginosa lineages during early infection in individuals with cystic fibrosis (CF). The Early Pseudomonas Infection Control Clinical Trial (EPIC-CT), which treated individuals with CF and newly detected P. aeruginosa infections, presents an ideal opportunity to study this phenomenon. METHODS: We performed whole-genome sequencing on 572 P. aeruginosa...
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