Article

Evolutionary Highways to Persistent Bacterial Infection

2018-05-18

Abstract excerpt

<h4>ABSTRACT</h4> Persistent infections require bacteria to evolve from their naïve colonization state by optimizing fitness in the host. This optimization involves coordinated adaptation of multiple traits, obscuring evolutionary trends and complicating infection management. Accordingly, we screen 8 infection-relevant phenotypes of 443 longitudinal Pseudomonas aeruginosa isolates from 39 young cystic fibrosis p...

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Literature Corpus work: 01d691e9-d6e8-5841-8f08-04c1e0d5a108
DOI: 10.1101/326025

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