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Article

Impact of CFTR Modulation on Pseudomonas aeruginosa Infection in People With Cystic Fibrosis.

The Journal of infectious diseases - 23 Sept 2024

Ledger Emma L, Smith Daniel J, Teh Jing Jie, Wood Michelle E, Whibley Page E, Morrison Mark, Goldberg Joanna B, Reid David W, Wells Timothy J

Abstract excerpt

BACKGROUND: Pseudomonas aeruginosa is a multidrug-resistant pathogen causing recalcitrant pulmonary infections in people with cystic fibrosis (pwCF). Cystic fibrosis transmembrane conductance regulator (CFTR) modulators have been developed that partially correct the defective chloride channel driving disease. Despite the many clinical benefits, studies in adults have demonstrated that while P. aeruginosa sputum...

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Identifiers

PMID: 38442240
DOI: 10.1093/infdis/jiae051
PMCID: PMC11420785

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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