Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Clinicopathological characterization of female genital tract cancers with STK11 alterations: redefining the spectrum beyond STK11 adnexal tumors.

Virchows Archiv : an international journal of pathology - 1 May 2026

Bao Longnv, Kong Weimao, Pan Xingzhu, Wang Jigang

Abstract excerpt

STK11 mutation is rarely reported in gynecologic malignancies. In addition to STK11 adnexal tumors, STK11 mutation can also be detected in other common types. The present study aims to investigate the clinicopathologic and prognostic features of female genital tract cancers with STK11 alterations. The authors retrospectively analyzed 13 cases of female genital tract cancers with STK11 alterations that underwent...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged, 80 and over
Share to AMP-Activated Protein Kinase Kinases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Aurora Kinase A

Share to Biomarkers, Tumor

Share to Genital Neoplasms, Female

Share to Germ-Line Mutation

Share to Ovarian Neoplasms

Share to Prognosis

Source

Identifiers

PMID: 41143909
DOI: 10.1007/s00428-025-04316-x

Genes

STK11
TP53
ATM
BRCA1
MLH1
MSH2
MSH6
PMS2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Clinicopathological characterization of female genital tract cancers with STK11 alterations: redefining the spectrum beyond STK11 adnexal tumors.PMID 41143909Read ↗

Serine/threonine kinase 11 (STK11) associated adnexal tumors: from biology to therapeutic impact.Semantic proximity Read ↗

Malignant STK11 adnexal tumor harboring a somatic mutation in a woman previously diagnosed with mesothelioma, a case reportSemantic proximity Read ↗

Landscape of somatic mutated genes and inherited susceptibility genes in gynecological cancer.Semantic proximity Read ↗

Society of Gynecologic Oncology statement on risk assessment for inherited gynecologic cancer predispositions.Semantic proximity Read ↗

Molecular Pathways and Targeted Therapies for Malignant Ovarian Germ Cell Tumors and Sex Cord–Stromal Tumors: A Contemporary ReviewSemantic proximity Read ↗

Clinical Pathological Feature Analysis and Prognostic Value Exploration of BRCA1/2 Exon11 MutationExon 11 Mutations in Patients with Gynecological MalignanciesSemantic proximity Read ↗

Genomic alterations in STK11 can predict clinical outcomes in cervical cancer patientsSemantic proximity Read ↗

Analysis of the genomic landscape of yolk sac tumors reveals mechanisms of evolution and chemoresistance.Semantic proximity Read ↗

Clinicopathologic and Molecular Analysis of Malignant Neoplasms With Yolk Sac Tumor Differentiation in Women 40 Years of Age and OlderSemantic proximity Read ↗

Everolimus plus anastrozole for female adnexal tumor of probable Wolffian origin (FATWO) with STK11 mutationSemantic proximity Read ↗

ALPK1 hotspot mutation as a driver of human spiradenoma and spiradenocarcinomaSemantic proximity Read ↗

Ovarian carcinomas: at least five different diseases with distinct histological features and molecular genetics.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.