Impact of IFITM3 rs12252 and IFNAR2 rs2236757 SNP polymorphisms on influenza virus infection outcomes in Moroccan patients.

doi:10.1007/s11033-025-11144-4

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Impact of IFITM3 rs12252 and IFNAR2 rs2236757 SNP polymorphisms on influenza virus infection outcomes in Moroccan patients.

Molecular biology reports - 23 Oct 2025

Ihazmade Hassan, Regragui Zakia, Bimouhen Abderrahman, Falaki Fatima El, Benkerroum Samira, Remz Chaimae, Elharti Elmir, Triki Soumia, Sadki Khalid, Oumzil Hicham

Abstract excerpt

BACKGROUND: Seasonal influenza is a crucial public health concern. Recent populationalstudies, confirmed the involvement of several signaling proteins on the outcome of theinfection. The IFITM3 and IFNAR2 variants, play acritical role in the host’sinnate immune response.The current study aims to evaluate the association between the IFITM3 rs12252 and IFNAR2rs2236757 variants with the risk of developing Severe...

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PMID: 41128776
DOI: 10.1007/s11033-025-11144-4

Genes

IFITM3
IFNAR2

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Impact of IFITM3 rs12252 and IFNAR2 rs2236757 SNP polymorphisms on influenza virus infection outcomes in Moroccan patients.PMID 41128776Read ↗

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