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Article

Cancer Incidence Rates Between BRCA1/2 Pathogenic Variant Carriers and Non-Carriers in Real-World Clinical Practice.

The Tohoku journal of experimental medicine - 2 Jun 2026

Ebata Akiko, Tada Hiroshi, Harada-Shoji Narumi, Hamanaka Yohei, Miyashita Minoru, Sato Miku, Ishida Takanori

Abstract excerpt

Since BRCA1/2 genetic testing has been covered by public insurance for certain breast cancer patients in Japan from April 2020, it has led to a rapid increase in testing frequency and the identification of many BRCA1/2 pathogenic variant (PV) carriers. BRCA1/2 PV carriers in Japan are reported to be also more susceptible to esophageal, gastric, and biliary tract cancers. We retrospectively analyzed 337 breast...

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Identifiers

PMID: 41093592
DOI: 10.1620/tjem.2025.J114

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BRCA1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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