Article
Reclassification of BRCA1 and BRCA2 variants found in ovarian epithelial, fallopian tube, and primary peritoneal cancers.
Journal of gynecologic oncology - 1 Nov 2020
Ha Hyeong In, Ryu Jin Sun, Shim Hyoeun, Kong Sun Young, Lim Myong Cheol
Abstract excerpt
OBJECTIVE: We investigated the proportions of and reclassified BRCA1/2 variants of unknown significance (VUS) in Korean patients with epithelial ovarian, tubal, and primary peritoneal cancers. METHODS: Data from 805 patients who underwent genetic testing for BRCA1/2 from January 1, 2006 to August 31, 2018 were included. The VUS in BRCA1/2 were reclassified using the 2015 American College of Medical Genetics and...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
