Article
Population-specific Mutation Patterns in Breast Tumors from African American, European American, and Kenyan Patients.
Cancer research communications - 7 Nov 2023
Tang Wei, Zhang Flora, Byun Jung S, Dorsey Tiffany H, Yfantis Harris G, Ajao Anuoluwapo, Liu Huaitian, Pichardo Margaret S, Pichardo Catherine M, Harris Alexandra R, Yang Xiaohong R, Figueroa Jonine D, Sayed Shahin, Makokha Francis W, Ambs Stefan
Abstract excerpt
Women of African descent have the highest breast cancer mortality in the United States and are more likely than women from other population groups to develop an aggressive disease. It remains uncertain to what extent breast cancer in Africa is reminiscent of breast cancer in African American or European American patients. Here, we performed whole-exome sequencing of genomic DNA from 191 breast tumor and...
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