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ApoE Polymorphism Analysis in Health and Disease of South Asian Populations: A Systematic Review and Meta-Analysis.

Clinical genetics - 1 Dec 2025

Paudel Prayash, Sah Asutosh, Paudel Poonam

Abstract excerpt

This systematic review and meta-analysis assesses the distribution and health implications of apolipoprotein E (ApoE) ε2, ε3, and ε4 alleles, which play crucial roles in lipoprotein metabolism, in South Asian populations, with a focus on neurodegenerative diseases, movement disorders, traumatic brain injury, mental health disorders, cardiovascular disorders, metabolic disorders, and trauma-related disorders. A...

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PMID: 41078217
DOI: 10.1111/cge.70064

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