Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic screens of imaging-derived kidney volumes identify genes linked to kidney function.

Kidney international - 1 Feb 2026

Monteiro-Martins Sara, Li Yong, Borisov Oleg, Khan Atlas, Reichardt Wilfried, Haug Stefan, Kellner Elias, Buechert Martin, Ott Elisabeth, Russe Maximilian F, Bamberg Fabian, Kiryluk Krzysztof, Sekula Peggy, Reisert Marco, Köttgen Anna

Abstract excerpt

INTRODUCTION: Chronic kidney disease (CKD) is defined as sustained abnormalities in kidney function or structure. Genetic studies of CKD have largely focused on kidney function markers such as estimated glomerular filtration rate (eGFR). We hypothesized that genome-wide association studies (GWAS) of magnetic resonance imaging (MRI)-based kidney sub-volumes could provide insights into CKD risk genes complementary...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genetic Testing
Share to Genome-Wide Association Study

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Glomerular Filtration Rate

Share to Kidney

Share to Magnetic Resonance Imaging

Share to Organ Size

Share to Renal Insufficiency, Chronic

Share to United Kingdom

Source

Open in PubMed Open full text

Identifiers

PMID: 41077127
DOI: 10.1016/j.kint.2025.08.038
PMCID: PMC13333066

Genes

BICC1
PKHD1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic screens of imaging-derived kidney volumes identify genes linked to kidney function.PMID 41077127Read ↗

Genomics of kidney volumes: one size does not fit all.Semantic proximity Read ↗

Genome-Wide Association Studies of CKD and Related Traits.Semantic proximity Read ↗

Trans-ethnic kidney function association study reveals putative causal genes and effects on kidney-specific disease aetiologiesSemantic proximity Read ↗

A catalog of genetic loci associated with kidney function from analyses of a million individualsSemantic proximity Read ↗

Trans-ethnic genome-wide association study of kidney function provides novel insight into effector genes and causal effects on kidney-specific disease aetiologiesSemantic proximity Read ↗

Sex-specific and pleiotropic effects underlying kidney function identified from GWAS meta-analysisSemantic proximity Read ↗

New loci associated with kidney function and chronic kidney diseaseSemantic proximity Read ↗

Multiple new genetic loci associated with kidney function and Chronic Kidney Disease: The CKDGen ConsortiumSemantic proximity Read ↗

Integration of GWAS Summary Statistics and Gene Expression Reveals Target Cell Types Underlying Kidney Function TraitsSemantic proximity Read ↗

Transcriptome- and proteome-wide association studies nominate determinants of kidney function and damageSemantic proximity Read ↗

Multimodal predictions of end stage chronic kidney disease from asymptomatic individuals for discovery of genomic biomarkersSemantic proximity Read ↗

Sex-specific and pleiotropic effects underlying kidney function identified from GWAS meta-analysisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.