Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

From risk to chronicity: genetic and neuroimaging insights into the evolving patterns of spontaneous brain activity in schizophrenia.

Psychological medicine - 10 Oct 2025

Zhang Yijing, Wang He, Cai Mengjing, Wang Wei, Qiao Jin, Wang Xinyu, Wu Yue, Wu Qian, Zhang Zhihui, Lei Minghuan, An Qi, Cai Wenjie, Wang Haolin, Li Fengtan, Xie Yingying, Liu Feng, Guo Lining

Abstract excerpt

BACKGROUND: Schizophrenia progresses through high-risk, first-episode, and chronic stages, each associated with altered spontaneous brain activity. Resting state functional MRI studies highlight these changes, but inconsistencies persist, and the genetic basis remains unclear. METHODS: A neuroimaging meta-analysis was conducted to assess spontaneous brain activity alterations in each schizophrenia stage. The...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Brain
Share to Chronic Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Disease Progression

Share to Genetic Predisposition to Disease

Share to Genome-Wide Association Study

Share to Magnetic Resonance Imaging

Share to Neuroimaging

Share to Schizophrenia

Source

Open in PubMed Open full text

Identifiers

PMID: 41069013
DOI: 10.1017/S0033291725102006
PMCID: PMC12551581

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

From risk to chronicity: genetic and neuroimaging insights into the evolving patterns of spontaneous brain activity in schizophrenia.PMID 41069013Read ↗

NeuroMark-SZ: A Holistic Resting-State-fMRI-Based Model for Divergent Functional Circuitry in SchizophreniaSemantic proximity Read ↗

Resting-state brain functional alterations and their genetic mechanisms in drug-naive first-episode psychosisSemantic proximity Read ↗

Neurofunctional aberrations associated with social cognition across clinical and genetic risk groups for schizophrenia: a meta-analysis of fMRI studies.Semantic proximity Read ↗

Brain transcriptome-wide association study implicates novel risk genes underlying schizophrenia risk.Semantic proximity Read ↗

Structural and functional brain abnormalities in schizophrenia: A cross-sectional study at different stages of the disease.Semantic proximity Read ↗

Multivariate analysis reveals genetic associations of the resting default mode network in psychotic bipolar disorder and schizophrenia.Semantic proximity Read ↗

Impact of schizophrenia-associated risk genes on brain functional networks and executive deficits: a study of individuals with schizophrenia and genetic high risk.Semantic proximity Read ↗

Structure–function coupling changes in first-episode, treatment-naïve schizophrenia correlate with cell type-specific transcriptional signatureSemantic proximity Read ↗

Associating Multimodal Neuroimaging Abnormalities With the Transcriptome and Neurotransmitter Signatures in SchizophreniaSemantic proximity Read ↗

Functional neuroimaging effects of recently discovered genetic risk loci for schizophrenia and polygenic risk profile in five RDoC subdomains.Semantic proximity Read ↗

Refining Schizophrenia Risk Assessment: Machine Learning Delineates a Brain Signature of Cognitive Basic SymptomsSemantic proximity Read ↗

Individual Brain Structure Deviations and its Gene Expression Signatures in Early-Onset SchizophreniaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.