Article
A protective effect of the BDNF Met/Met genotype in obesity in healthy Caucasian subjects but not in patients with coronary heart disease.
European review for medical and pharmacological sciences - 1 Aug 2016
Sustar A, Nikolac Perkovic M, Nedic Erjavec G, Svob Strac D, Pivac N
Abstract excerpt
OBJECTIVE: Brain-derived neurotrophic factor (BDNF) is a neurotrophic factor with an important role in the regulation of body weight, body mass index (BMI) and obesity. Increased BMI that leads to obesity is a substantial risk factor for coronary heart disease (CHD). The functional BDNF Val66Met polymorphism (rs6265) has been associated with CHD, obesity and BMI. The aim of the study was to determine the...
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