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Article

Multiple-testing corrections in selection scans using identity-by-descent segments.

American journal of human genetics - 6 Nov 2025

Temple Seth D, Browning Sharon R

Abstract excerpt

Failing to correct for multiple testing in selection scans can lead to false discoveries of recent genetic adaptations. The scanning statistics in selection studies are often too complicated to theoretically derive a genome-wide significance level or empirically validate control of the family-wise error rate (FWER). By modeling the autocorrelation of identity-by-descent (IBD) rates, we propose a computationally...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 41015036
DOI: 10.1016/j.ajhg.2025.09.004
PMCID: PMC12668784

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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