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Article

Altered Expression of m6A-Associated Genes Is Linked with Poor Prognosis in Pediatric Acute Myeloid Leukemia Patients.

Biomolecules - 27 Aug 2025

Kaur Parminder, Rajitha Bollipogu, Jain Richa, Sharma Pankaj, Bhatia Prateek, Naseem Shano, Trehan Amita, Singh Minu

Abstract excerpt

The dysregulation of m6A-related genes recognized as 'writers', 'readers', and 'erasers' is reported to be involved in the initiation, progression, and drug resistance of acute myeloid leukemia (AML). In the present study, we investigated the expression levels of various readers, writers, and erasers in pediatric AML patients. Additionally, we categorized the patients according to the molecular subtyping of...

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Share to Child, Preschool
Share to Gene Expression Regulation, Leukemic

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Share to Leukemia, Myeloid, Acute

Share to Methyltransferases

Share to Nucleophosmin

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Source

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Identifiers

PMID: 41008545
DOI: 10.3390/biom15091238
PMCID: PMC12467299

Genes

YTHDF1
YTHDF2
ALKBH5
FLT3
FTO
METTL14
METTL3
NPM1
RBM15

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 10 Sept 2026.

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