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Article

m6A genotypes and prognostic signature for assessing the prognosis of patients with acute myeloid leukemia.

BMC medical genomics - 18 Aug 2023

Fu Caizhu, Kou Ruirui, Meng Jie, Jiang Duanfeng, Zhong Ruilan, Dong Min

Abstract excerpt

BACKGROUND: N6-methyladenosine (m6A) has been confirmed to function critically in acute myeloid leukemia (AML) progression. Hitherto, the subtyping and prognostic predictive significance of m6A-correlated genes in AML is unclear. METHOD: From The Cancer Genome Atlas (TCGA-LAML), Therapeutically Applicable Research to Generate Effective Treatments (TARGET-AML) and Gene Expression Omnibus (GEO, GSE71014) databases,...

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PMID: 37596597
DOI: 10.1186/s12920-023-01629-1
PMCID: PMC10436408

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