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Article

Adaptation to cinnamaldehyde shapes Pseudomonas aeruginosa resistance to major antibiotics.

Journal of bacteriology - 23 Oct 2025

Dubois Eline, Gaillot Susie, Valot Benoît, Bour Maxime, Brunel Jean-Michel, Schmidlin Lison, Plésiat Patrick, Llanes Catherine

Abstract excerpt

In France, the use of essential oils to treat bacterial infections is common, with approximately 40% of cystic fibrosis patients regularly using these natural products to control infections caused by Pseudomonas aeruginosa often in combination with their antibiotic treatments. Previous research has demonstrated that prolonged exposure of P. aeruginosa PA14 to cinnamaldehyde (CNA), the main component of cinnamon...

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Identifiers

PMID: 41004622
DOI: 10.1128/jb.00180-25
PMCID: PMC12548396

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