Article
Genetic Susceptibility to Neurodevelopmental Conditions Is Associated With Neonatal DNA Methylation Patterns in the General Population: An Individual Participant Data Meta-Analysis.
Biological psychiatry - 15 Aug 2026
Schuurmans Isabel K, Smajlagic Dinka, Baltramonaityte Vilte, Malmberg Anni L K, Neumann Alexander, Creasey Nicole, Felix Janine F, Tiemeier Henning, Pingault Jean-Baptiste, Czamara Darina, Raïkkönen Katri, Page Christian Magnus, Lyle Robert, Havdahl Alexandra, Lahti Jari, Walton Esther, Bekkhus Mona, Cecil Charlotte A M
Abstract excerpt
BACKGROUND: Autism spectrum disorder (ASD), attention-deficit/hyperactivity disorder (ADHD), and schizophrenia (SCZ) are highly heritable and linked to disruptions in fetal neurodevelopment. Epigenetic processes, such as DNA methylation (DNAm), are considered a key pathway of interest. However, it is unclear whether 1) genetic susceptibility to neurodevelopmental conditions (NDCs) is associated with DNAm patterns...
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